BDBM50079176 1-(1-Benzyl-piperidin-4-yl)-4-(4-methoxy-phenyl)-5-methyl-1,3-dihydro-imidazol-2-one::CHEMBL450021

SMILES COc1ccc(cc1)-c1[nH]c(=O)n(C2CCN(Cc3ccccc3)CC2)c1C

InChI Key InChIKey=JSOOBIHCFROWDG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079176   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079176(1-(1-Benzyl-piperidin-4-yl)-4-(4-methoxy-phenyl)-5...)
Affinity DataKi:  12nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D4 stably expressed in HEK393 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079176(1-(1-Benzyl-piperidin-4-yl)-4-(4-methoxy-phenyl)-5...)
Affinity DataKi:  110nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D2 stably expressed in CHO cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079176(1-(1-Benzyl-piperidin-4-yl)-4-(4-methoxy-phenyl)-5...)
Affinity DataKi:  360nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D3 (hD3) stably expressed in HEK393 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed