BDBM50079181 1-(1-Benzyl-piperidin-4-yl)-3,5-dimethyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL328739

SMILES Cc1c(-c2ccccc2)n(C)c(=O)n1C1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=BXEHOLVBINGZIE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079181   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079181(1-(1-Benzyl-piperidin-4-yl)-3,5-dimethyl-4-phenyl-...)
Affinity DataKi:  0.75nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D4 stably expressed in HEK393 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079181(1-(1-Benzyl-piperidin-4-yl)-3,5-dimethyl-4-phenyl-...)
Affinity DataKi:  15nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D2 stably expressed in CHO cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079181(1-(1-Benzyl-piperidin-4-yl)-3,5-dimethyl-4-phenyl-...)
Affinity DataKi:  140nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D3 (hD3) stably expressed in HEK393 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed