BDBM50079510 CHEMBL3417302

SMILES Cc1cc(=O)oc2cc(OCCN3CCN(CCCNc4c5CCCCc5nc5ccccc45)CC3)ccc12

InChI Key InChIKey=SMGUTCNZXGIUCJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50079510   

TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50079510(CHEMBL3417302)
Affinity DataIC50: 39nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 6 mins prior to substrate addition measured after 60 to 180...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50079510(CHEMBL3417302)
Affinity DataIC50: 51nMAssay Description:Inhibition of horse serum BuChE using S-butyrylthiocholine iodide as substrate incubated for 6 mins prior to substrate addition measured after 60 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50079510(CHEMBL3417302)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate assessed as H2O2 production by amplex red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50079510(CHEMBL3417302)
Affinity DataIC50: 6.67E+4nMAssay Description:Inhibition of human MAO-A using p-tyramine as substrate assessed as H2O2 production by amplex red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed