BDBM50079641 2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile::CHEMBL300553

SMILES Clc1ccc(cc1)N1CCN(Cc2cc[nH]c2C=C(C#N)C#N)CC1

InChI Key InChIKey=RCACIEKJQOIDQV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50079641   

TargetD(4) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079641(2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...)
Affinity DataKi:  125nMAssay Description:Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079641(2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...)
Affinity DataKi:  7.60E+3nMAssay Description:Ability to displace [3H]spiperone from the cloned human D3 dopamine receptor stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079641(2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...)
Affinity DataKi:  8.95E+3nMAssay Description:Ability to displace [3H]spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079641(2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...)
Affinity DataKi:  1.35E+4nMAssay Description:Ability to displace D1 selective radioligand [3H]-SCH- 23390 in bovine striatal membrane preparations was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079641(2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...)
Affinity DataKi:  1.50E+4nMAssay Description:Ability to displace [3H]spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed