BDBM50079643 2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile::CHEMBL440120

SMILES N#CC(=Cc1[nH]ccc1CN1CCN(CC1)c1ccccc1)C#N

InChI Key InChIKey=JXPFVJLJUKGXQP-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50079643   

TargetD(4) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079643(2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...)
Affinity DataKi:  160nMAssay Description:Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079643(2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...)
Affinity DataKi:  4.00E+3nMAssay Description:Ability to displace [3H]spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079643(2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...)
Affinity DataKi:  6.95E+3nMAssay Description:Ability to displace [3H]spiperone from the cloned human D3 dopamine receptor stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079643(2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...)
Affinity DataKi:  1.28E+4nMAssay Description:Ability to displace [3H]spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
UniversitäT Erlangen - NüRnberg

Curated by ChEMBL
LigandPNGBDBM50079643(2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...)
Affinity DataKi:  2.20E+4nMAssay Description:Ability to displace D1 selective radioligand [3H]-SCH- 23390 in bovine striatal membrane preparations was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed