BDBM50079899 3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-carbonitrile::3-Trifluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile::CHEMBL112038

SMILES FC(F)(F)C1Cc2ccc(cc2CN1)C#N

InChI Key InChIKey=FQMARIFLTAAEKA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50079899   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079899(3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079899(3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of PNMT (Phenylethanolamine N-Methyltransferase) in vitro More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079899(3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibitory activity against human PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50079899(3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline...)
Affinity DataKi:  2.90E+6nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed