BDBM50079902 7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoquinoline::7-bromo-3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL112964

SMILES FC(F)(F)C1Cc2ccc(Br)cc2CN1

InChI Key InChIKey=PEEKNBLYJJEHJI-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50079902   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079902(7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  520nMAssay Description:Inhibition of PNMT (Phenylethanolamine N-Methyltransferase) in vitro More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079902(7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  520nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079902(7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  520nMAssay Description:Affinity for bovine Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079902(7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibitory activity against human PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079902(7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human PNMT by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50079902(7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  4.35E+3nMAssay Description:Binding affinity against human alpha 2A adrenergic receptor in CHO cells using [3H]RX-821002 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50079902(7-Bromo-3-trifluoromethyl-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  1.00E+6nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed