BDBM50081158 2-((R)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((S)-1-carbamimidoyl-2-hydroxy-piperidin-3-yl)-acetamide::CHEMBL314914::CHEMBL79422

SMILES NC(=N)N1CCC[C@H](NC(=O)CN2CCC[C@@](N)(Cc3ccccc3)C2=O)C1O

InChI Key InChIKey=MJWDBCUSOIFRIS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081158   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081158(CHEMBL79422 | CHEMBL314914 | 2-((R)-3-Amino-3-benz...)
Affinity DataKi:  1nMAssay Description:Evaluation of inhibition of transition state thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081158(CHEMBL79422 | CHEMBL314914 | 2-((R)-3-Amino-3-benz...)
Affinity DataIC50: 2.10nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081158(CHEMBL79422 | CHEMBL314914 | 2-((R)-3-Amino-3-benz...)
Affinity DataIC50: 139nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article