BDBM50081537 CHEMBL3422092
SMILES [H][C@]12CC[C@@]([H])(CC(O)C1)N2c1ccc(cc1)-c1n[nH]c2ccc(cc12)C(=O)N[C@H](C1CC1)c1ccccn1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50081537
Affinity DataKi: 0.700nMAssay Description:Competitive inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate by Lineweaver-Burk plot analysis in prese...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate preincubated for 15 mins prior to ATP addition by ind...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of human Ret V804L mutant by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of human Ret V804M mutant by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human Ret by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of human JNK3 by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human MAPK1 by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of human MELK by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of human MuSK by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of PLK4 (unknown origin) by indirect ELISA detection systemMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of TTK (unknown origin) transfected in human HCT116 cells after 4 hrs by near infrared imager analysisMore data for this Ligand-Target Pair
Affinity DataEC50: >6.00E+3nMAssay Description:Inhibition of AURKA (unknown origin) transfected in human HCT116 cells after 4 hrs by near infrared imager analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant AURKA (unknown origin) preincubated for 15 mins prior to ATP addition by FRET-based homogenous assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human CYP3A4 using BFC as substrate preincubated for 10 mins followed by enzyme/substrate addition measured after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP3A4 using BFC as substrate preincubated for 10 mins followed by enzyme/substrate addition measured after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate preincubated for 15 mins prior to ATP addition by ind...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of human cKit V560G mutant by millipore radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human cKit by millipore radiometric assayMore data for this Ligand-Target Pair