BDBM50082208 CHEMBL3421739

SMILES COc1ccc(cc1)-c1noc(CNCc2ccc(cc2)C(=O)Nc2ccccc2N)n1

InChI Key InChIKey=OEIWOBHSMWRABY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082208   

TargetHistone deacetylase 1(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50082208(CHEMBL3421739)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50082208(CHEMBL3421739)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50082208(CHEMBL3421739)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed