BDBM50082211 CHEMBL3421742

SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2nc(no2)-c2ccc(cc2)[N+]([O-])=O)cc1

InChI Key InChIKey=BDRCYQNCRYTWTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082211   

TargetHistone deacetylase 1(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50082211(CHEMBL3421742)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50082211(CHEMBL3421742)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50082211(CHEMBL3421742)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed