BDBM50082393 CHEMBL441075::piperidine based analogue of cocaine

SMILES CN1CC[C@@H]([C@H](CCCN2CCS[Re]3(=O)SCCN3CC2)C1)c1ccc(Cl)cc1

InChI Key InChIKey=MOSBZMKCELQGIW-UHFFFAOYSA-L

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082393   

TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  96nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]mazindol as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  193nMAssay Description:Inhibition of monoamine [3H]DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  231nMAssay Description:Norepinephrine transporter activity was determined by inhibition of monoamine [3H]-NE reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082393(piperidine based analogue of cocaine | CHEMBL44107...)
Affinity DataKi:  243nMAssay Description:Inhibition of monoamine [3H]5-HT reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed