BDBM50082395 (3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-piperidine::CHEMBL109097

SMILES CCC[C@@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1

InChI Key InChIKey=MWGRXFWGMDSMNI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082395   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082395((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 3nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082395((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 3nMAssay Description:Binding affinity against dopamine transporter (DAT) was evaluated using competitive binding assay and [3H]mazindol as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082395((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed