BDBM50082701 2-(3-Bromo-4-methoxy-phenyl)-5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-pentanenitrile::CHEMBL142468

SMILES COc1ccc(cc1Br)C(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)C#N

InChI Key InChIKey=ZIGSTFJZTOHULE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082701   

TargetC-C chemokine receptor type 1(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082701(2-(3-Bromo-4-methoxy-phenyl)-5-[4-(4-chloro-phenyl...)
Affinity DataKi:  74nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082701(2-(3-Bromo-4-methoxy-phenyl)-5-[4-(4-chloro-phenyl...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of MIP-1-alpha-induced intracellular calcium mobilization in HEK293 cells expressing human CCR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed