BDBM50082711 1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl)-piperidin-4-ol::CHEMBL125111

SMILES NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=MPEGRCNLPCPVSF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082711   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082711(1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl...)
Affinity DataKi:  244nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50082711(1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl...)
Affinity DataIC50:  760nMAssay Description:Inhibitory activity against human Chemokine receptor type 1 expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50082711(1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against recombinant human Chemokine receptor type 3 (CCR3) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed