BDBM50083104 CHEMBL343217::[(R)-1-(4-Fluoro-phenyl)-2-methoxy-ethyl]-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine

SMILES COC[C@H](NC1CCN(CCCc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=COUOPYDUWJXPLJ-MHZLTWQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083104   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083104(CHEMBL343217 | [(R)-1-(4-Fluoro-phenyl)-2-methoxy-...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083104(CHEMBL343217 | [(R)-1-(4-Fluoro-phenyl)-2-methoxy-...)
Affinity DataIC50:  89nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed