BDBM50083151 CHEMBL344537::[(R)-1-(4-Fluoro-phenyl)-2-methoxy-ethyl]-{1-[3-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine

SMILES COC[C@H](NC1CCN(CCCc2c[nH]c3ccc(Cn4cncn4)cc23)CC1)c1ccc(F)cc1

InChI Key InChIKey=YSUFYQOHSFXSTE-NDEPHWFRSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083151   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083151(CHEMBL344537 | [(R)-1-(4-Fluoro-phenyl)-2-methoxy-...)
Affinity DataEC50:  8.90nMAssay Description:Agonist-induced [35S]- GTPgammaS binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083151(CHEMBL344537 | [(R)-1-(4-Fluoro-phenyl)-2-methoxy-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083151(CHEMBL344537 | [(R)-1-(4-Fluoro-phenyl)-2-methoxy-...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed