BDBM50083411 1-Cyclohexyl-3-[1-(3H-imidazol-4-ylmethyl)-4-(naphthalene-1-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl]-urea::CHEMBL356905

SMILES O=C(NC1CCCCC1)Nc1ccc2CN(CCN(Cc3cnc[nH]3)c2c1)C(=O)c1cccc2ccccc12

InChI Key InChIKey=BTBGNYNSFZIXDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083411   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083411(1-Cyclohexyl-3-[1-(3H-imidazol-4-ylmethyl)-4-(naph...)
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed