BDBM50083621 (3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-(3-phenyl-propyl)-8-aza-bicyclo[3.2.1]octane

SMILES Fc1ccc(cc1)[C@@H]1CC2CCC(C1c1ccc(F)cc1)N2CCCc1ccccc1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083621   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083621((3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-(3-phenyl-prop...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]mazindol from cocaine binding site on Dopamine transporter (DAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083621((3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-(3-phenyl-prop...)
Affinity DataKi:  43nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083621((3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-(3-phenyl-prop...)
Affinity DataKi:  608nMAssay Description:Inhibition of [3H]5-HT uptake at striatal nerve endings by serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed