BDBM50083780 2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4-(pyridin-2-ylamino)-butyl]-4,5-dihydro-isoxazole-3-carbonyl}-amino)-propionic acid::CHEMBL129747

SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O)-c1ccccc1

InChI Key InChIKey=VJKWDOHVIUYNBB-JKGBFCRXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083780   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083780(2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083780(2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...)
Affinity DataIC50:  44nMAssay Description:Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed