BDBM50084208 (R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-tert-butoxyimino]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL151133

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC(C)(C)C

InChI Key InChIKey=FIAWLFURFKPROF-RHTHQAGFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084208   

Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084208((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-tert-butox...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloproteinase-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084208((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-tert-butox...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloproteinase-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084208((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-tert-butox...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084208((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-tert-butox...)
Affinity DataIC50:  294nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloproteinase-7, MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084208((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-tert-butox...)
Affinity DataIC50:  74nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed