BDBM50084289 (S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::CHEMBL44383

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)C(O)=O

InChI Key InChIKey=MDWFJTBWOFNAQX-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50084289   

Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 10.6nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 24.2nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 747nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 1.89E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 7.20E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 8.71E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-3-methyl-b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed