BDBM50085994 CHEMBL8970::N-{4-(Biphenyl-2-ylmethyl-isobutyl-amino)-1-[2-(2,4-difluoro-benzoyl)-benzoyl]-pyrrolidin-2-ylmethyl}-4-(2,4-dioxo-thiazolidin-5-ylidenemethyl)-benzamide

SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F

InChI Key InChIKey=LOMAZTFGYVJFGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085994   

TargetCytosolic phospholipase A2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50085994(N-{4-(Biphenyl-2-ylmethyl-isobutyl-amino)-1-[2-(2,...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed