BDBM50086674 6-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one::CHEMBL141184

SMILES OC(COc1ccc2SCC(=O)Nc2c1)CN1CCN(CC1)C(=O)c1ccco1

InChI Key InChIKey=OZSDSLANSUSJIQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50086674   

TargetBeta-1 adrenergic receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50086674(6-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Beta-1 adrenergic receptor binding affinity by measuring the displacement of [3H]dihydroalprenolol binding in rat heart; Not Active means Ki >1000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50086674(6-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-2 adrenergic receptor binding affinity by measuring the displacement of [3H]clonidine binding in rat cerebral cortex; Not Active means Ki >1000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50086674(6-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 adrenergic receptor binding affinity by measuring the displacement of [3H]-prazosin binding in rat brain; Not Active means Ki >1000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Dog)
Università

Curated by ChEMBL
LigandPNGBDBM50086674(6-{3-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-hydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Beta-2 adrenergic receptor binding affinity by measuring the displacement of [3H]DHA binding in rat lung; Not Active means Ki >1000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed