BDBM50087491 (Cis)2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione::CHEMBL288809

SMILES COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c([nH]c5ccccc54)c3=O)CC21

InChI Key InChIKey=WIRHRVAPDHCAEN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087491   

TargetAlpha-1D adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087491BDBM50087491((Cis)2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo...)
Affinity DataKi:  0.740nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1D adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087491BDBM50087491((Cis)2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo...)
Affinity DataKi:  0.790nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087491BDBM50087491((Cis)2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo...)
Affinity DataKi:  2.25nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1B adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed