BDBM50087493 7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2-methyl-5H-9-thia-1,4,5,7-tetraaza-fluorene-6,8-dione::CHEMBL297218

SMILES COc1cccc2c1CC[C@H]1CN(CCn3c(=O)[nH]c4c(sc5nc(C)cnc54)c3=O)C[C@@H]21

InChI Key InChIKey=UHWMKXZEHKUXCT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087493   

TargetAlpha-1A adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087493BDBM50087493(7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]is...)
Affinity DataKi:  0.490nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087493BDBM50087493(7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]is...)
Affinity DataKi:  2.31nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1D adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087493BDBM50087493(7-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]is...)
Affinity DataKi:  13.5nMAssay Description:In vitro binding affinity using [3H]prazosin as radioligand against alpha-1B adrenergic receptor expressed in LTK cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed