BDBM50087640 2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-2-(1-carbamimidoyl-piperidin-3-yl)-ethylsulfamoyl]-methyl}-benzoic acid methyl ester; TFA::CHEMBL352119

SMILES COC(=O)c1ccccc1CS(=O)(=O)N[C@H](CC1CCCN(C1)C(N)=N)C(=O)NCC(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key InChIKey=CWBPPDBIZLIFDM-UFFCEZGPSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50087640   

TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50:  1.95E+3nMAssay Description:In vitro inhibition of human plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50:  1.37nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50:  1.95E+3nMAssay Description:In vitro inhibition of human Coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human VCAM and Ramos cell VLA-4 interactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50087640(2-{[(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperid...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed