BDBM50087706 CHEMBL265847::Urotensin-1-sucker fish(NDDPPISIDLTFHLLRNMIEMARIENEREQAGLNRKYLDEV-NH2)

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)NC(CC(=O)O)C(=O)C(CC(=O)O)NC(=O)C(N)CC(N)=O)[C@@H](C)CC)[C@@H](C)CC)C(C)O)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(N)=O)C(C)C

InChI Key InChIKey=YIHRBRJTFIGRRV-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087706   

TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087706BDBM50087706(Urotensin-1-sucker fish(NDDPPISIDLTFHLLRNMIEMARIEN...)
Affinity DataKi:  1.07nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087706BDBM50087706(Urotensin-1-sucker fish(NDDPPISIDLTFHLLRNMIEMARIEN...)
Affinity DataKi:  1.26nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087706BDBM50087706(Urotensin-1-sucker fish(NDDPPISIDLTFHLLRNMIEMARIEN...)
Affinity DataEC50:  1.5nMAssay Description:Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087706BDBM50087706(Urotensin-1-sucker fish(NDDPPISIDLTFHLLRNMIEMARIEN...)
Affinity DataEC50:  6.30nMAssay Description:Activity of peptidic agonists on corticotropin releasing factor receptor using agonist-stimulated adenylate cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed