BDBM500881 (S)-7-((6- ((dimethylamino)- methyl)-5- (tetrahydrofuran- 3-yl)pyridin- 2-yl)amino)-4- (1-methyl-1H- pyrrolo[2,3- b]pyridin-4- yl)isoindolin- 1-one::US11021481, Compound I-545::US11078201, Compound I-545::US11548890, Compound I-545
SMILES CN(C)Cc1nc(Nc2ccc(c3CNC(=O)c23)-c2ccnc3n(C)ccc23)ccc1[C@@H]1CCOC1
InChI Key InChIKey=ACBDIEGHHWPOBF-QGZVFWFLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 500881
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair