BDBM50088171 CHEMBL3427248

SMILES Cc1noc(C)c1[C@@H]1C[C@H](N=C(N)S1)c1cc(cs1)-c1cccc(c1)C#N

InChI Key InChIKey=CEGMKFULIAKHNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088171   

TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088171(CHEMBL3427248)
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed