BDBM50088172 CHEMBL3427249

SMILES CC#Cc1cncc(c1)-c1csc(c1)[C@@H]1C[C@H](SC(N)=N1)c1c(C)noc1C

InChI Key InChIKey=JHXBUZHKTRBUPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088172   

TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088172(CHEMBL3427249)
Affinity DataIC50: 60nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed