BDBM50088176 CHEMBL3427253

SMILES Cc1noc(CC(C)(C)O)c1[C@@H]1C[C@](C)(N=C(N)S1)c1ccc(F)cc1F

InChI Key InChIKey=ACFHKZODPNAMLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088176   

TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088176(CHEMBL3427253)
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed