BDBM50088327 9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2-carboxylic acid methyl ester::CHEMBL294105

SMILES COC(=O)[C@H]1C2CC[C@@H]3C[C@@H]1\C(CN23)=C\c1ccccc1

InChI Key InChIKey=XTYJQBUILMRWGE-GZAGPRJLSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50088327   

TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  53nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  68nMAssay Description:Compound was evaluated for inhibition of [3H]NE uptake in HEK-hNET cells expressing Human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  481nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  910nMAssay Description:Compound was evaluated for inhibition of [3H]DA uptake in HEK-hDAT cells expressing Human dopamine TransporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  1.04E+3nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hNET cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  1.57E+3nMAssay Description:Compound was evaluated for binding affinity to dopamine transporter using [125I]RTI-55 as a radioligand in HEK cells expressing human transporters.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  2.33E+3nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hSERT cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  2.40E+3nMAssay Description:Compound was evaluated for inhibition of [3H]5-HT uptake in HEK-hSERT cells expressing Human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed