BDBM50088824 CHEMBL422212::Sodium; 5,5,8-trioxo-3-(2-phenoxy-acetoxymethyl)-7-[1-pyridin-2-yl-meth-(Z)-ylidene]-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

SMILES [O-]C(=O)C1=C(COC(=O)COc2ccccc2)CS(=O)(=O)C2N1C(=O)\C2=C\c1ccccn1

InChI Key InChIKey=PYWUADTVINPSEC-YVLHZVERSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088824   

TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088824(CHEMBL422212 | Sodium; 5,5,8-trioxo-3-(2-phenoxy-a...)
Affinity DataIC50:  130nMAssay Description:Inhibition of GC1 extended spectrum class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088824(CHEMBL422212 | Sodium; 5,5,8-trioxo-3-(2-phenoxy-a...)
Affinity DataIC50:  100nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088824(CHEMBL422212 | Sodium; 5,5,8-trioxo-3-(2-phenoxy-a...)
Affinity DataIC50:  800nMAssay Description:Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088824(CHEMBL422212 | Sodium; 5,5,8-trioxo-3-(2-phenoxy-a...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed