BDBM50089302 CHEMBL3577924

SMILES Cc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc2c(ncnc2s1)-c1ccncc1

InChI Key InChIKey=NPEDBEHZJZSTMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089302   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Pkucare Pharmaceutical R & D Center

Curated by ChEMBL
LigandPNGBDBM50089302(CHEMBL3577924)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2/PS as substrate after 1 hr by luciferase-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pkucare Pharmaceutical R & D Center

Curated by ChEMBL
LigandPNGBDBM50089302(CHEMBL3577924)
Affinity DataIC50: 345nMAssay Description:Inhibition of mTOR (unknown origin) using GFP-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed