BDBM50089645 CHEMBL3576987

SMILES COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=VRKFCJLHHOKPIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089645   

TargetProstaglandin G/H synthase 2(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089645(CHEMBL3576987)
Affinity DataIC50: 6.61E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGF2 alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089645(CHEMBL3576987)
Affinity DataIC50: 6.55E+4nMAssay Description:Inhibition of ovine COX-1 assessed as PGF2alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior to substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed