BDBM50089647 CHEMBL3576982

SMILES COC(=O)CC[C@@H](NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1)C(=O)OC

InChI Key InChIKey=HUQKHTMNNVJCEH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089647   

TargetProstaglandin G/H synthase 2(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089647(CHEMBL3576982)
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGF2 alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089647(CHEMBL3576982)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of ovine COX-1 assessed as PGF2alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior to substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed