BDBM50089652 CHEMBL3576980

SMILES Cc1ccc(cc1)S(=O)(=O)n1cc(C(=O)C(=O)NCC(=O)N[C@H](Cc2c[nH]c3ccccc23)C(O)=O)c2ccccc12

InChI Key InChIKey=MSUCZAQRBMNZKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089652   

TargetProstaglandin G/H synthase 2(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089652(CHEMBL3576980)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGF2 alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50089652(CHEMBL3576980)
Affinity DataIC50: 9.83E+4nMAssay Description:Inhibition of ovine COX-1 assessed as PGF2alpha formation using arachidonic acid as substrate pretreated with compound for 20 mins prior to substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed