BDBM50090003 CHEMBL405190::Tyr-Gly-[D-Ala]-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::[D-Ala-3] Dynorphin A (1-11)-NH2H-Tyr-Gly-D-Ala-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2
SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(N)=O
InChI Key InChIKey=AQXYHKIZMZEAGF-ZKSYIDMUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50090003
Affinity DataKi: 0.150nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
Affinity DataKi: 407nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
Affinity DataEC50: 6.10nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Agonistic activity towards Opioid receptors in the guinea pig ileumMore data for this Ligand-Target Pair