BDBM50090048 6-Butyl-1-(4-chloro-phenyl)-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL90292

SMILES CCCCC1N=C(N)N=C(N)N1c1ccc(Cl)cc1

InChI Key InChIKey=VWHBREVXFNULBX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090048   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum)
National Center For Genetic Engineering and Biotechnology At Thailand

Curated by ChEMBL
LigandPNGBDBM50090048(6-Butyl-1-(4-chloro-phenyl)-1,6-dihydro-[1,3,5]tri...)
Affinity DataKi:  3.70nMAssay Description:Evaluated for inhibition constant (Ki wt) against Wild-type dihydrofolate reductase of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase [A16V,S108T](Plasmodium falciparum)
National Center For Genetic Engineering and Biotechnology At Thailand

Curated by ChEMBL
LigandPNGBDBM50090048(6-Butyl-1-(4-chloro-phenyl)-1,6-dihydro-[1,3,5]tri...)
Affinity DataKi:  167nMAssay Description:Evaluated for inhibition constant (Ki mut) against A16V+S108T Mutant dihydrofolate reductase of Plasmodium falciparumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed