BDBM50090067 6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL6742
SMILES CC1(C)N=C(N)N=C(N)N1c1ccccc1
InChI Key InChIKey=VMVKLCXTXSSZSI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50090067
Affinity DataKi: 2.60nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum)
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Evaluated for inhibition constant (Ki wt) against Wild-type dihydrofolate reductase of Plasmodium falciparumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibition constant against Plasmodium falciparum dihydrofolate reductaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 204nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 309nMAssay Description:Inhibition of dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [A16V,S108T](Plasmodium falciparum)
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 1.38E+3nMAssay Description:Inhibition constant (Ki mut) against A16V+S108T Mutant DHFRs of Plasmodium falciparumMore data for this Ligand-Target Pair
Affinity DataKi: 1.66E+3nMAssay Description:Inhibition of human dihydrofolate reductase (DHFR) enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 1.66E+3nMAssay Description:Inhibitory activity against human lymphoblastoid cell (WIL2) dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Leishmania major)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.26E+4nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 3.09E+4nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.09E+4nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair