BDBM50090303 CHEMBL42220::N-{3-[4-Cyano-4-(2-methoxy-phenyl)-piperidin-1-yl]-propyl}-2,2-di-p-tolyl-acetamide

SMILES COc1ccccc1C1(CCN(CCCNC(=O)C(c2ccc(C)cc2)c2ccc(C)cc2)CC1)C#N

InChI Key InChIKey=CGCLDRKORPAFBZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090303   

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50090303(N-{3-[4-Cyano-4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50090303(N-{3-[4-Cyano-4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataKi:  570nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50090303(N-{3-[4-Cyano-4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataKi:  710nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed