BDBM50090310 CHEMBL44294::N-{3-[4-(2-Chloro-phenyl)-4-cyano-piperidin-1-yl]-propyl}-2,2-di-p-tolyl-acetamide

SMILES Cc1ccc(cc1)C(C(=O)NCCCN1CCC(CC1)(C#N)c1ccccc1Cl)c1ccc(C)cc1

InChI Key InChIKey=CXSHNGLATCDICJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090310   

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50090310(N-{3-[4-(2-Chloro-phenyl)-4-cyano-piperidin-1-yl]-...)
Affinity DataKi:  0.990nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50090310(N-{3-[4-(2-Chloro-phenyl)-4-cyano-piperidin-1-yl]-...)
Affinity DataKi:  280nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50090310(N-{3-[4-(2-Chloro-phenyl)-4-cyano-piperidin-1-yl]-...)
Affinity DataKi:  600nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed