BDBM500907 7-((5-((2R,5S)-2- (hydroxymeth- yl)-5-methoxy-piperidin- 1-yl)pyridin-2- yl)amino)-4- (4,5,6,7- tetrahydropyra- zolo[1,5-a]pyridin-3- yl)isoindolin- 1-one::US11021481, Compound I-571::US11548890, Compound I-571
SMILES CO[C@H]1CC[C@H](CO)N(C1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnn3CCCCc23)nc1
InChI Key InChIKey=WXJBDULULMAKJM-MOPGFXCFSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 500907
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair