BDBM500908 7-((5-((2R,5R)-2- (hydroxymeth- yl)-5-methoxy-piperidin-1- yl)pyridin-2- yl)amino)-4- (4,5,6,7- tetraln dropyra- zolo[1,5- a]pyridin-3- yl)isoindolin- 1-one::US11021481, Compound I-572::US11548890, Compound I-572

SMILES CO[C@@H]1CC[C@@H](CO)N(C1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnn3CCCCc23)nc1

InChI Key InChIKey=WXJBDULULMAKJM-RBUKOAKNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 500908   

LigandPNGBDBM500908(7-((5-((2R,5R)-2- (hydroxymeth- yl)-5-methoxy-pipe...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500908(7-((5-((2R,5R)-2- (hydroxymeth- yl)-5-methoxy-pipe...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500908(7-((5-((2R,5R)-2- (hydroxymeth- yl)-5-methoxy-pipe...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500908(7-((5-((2R,5R)-2- (hydroxymeth- yl)-5-methoxy-pipe...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent