BDBM50090963 CHEMBL3582018::US9290451, 86

SMILES CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC

InChI Key InChIKey=JVMZQMRYIYTXKO-UHFFFAOYSA-N

Data  2 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50090963   

TargetCannabinoid receptor 2(Human)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50090963(US9290451, 86 | CHEMBL3582018)
Affinity DataEC50:  4.30nMAssay Description:Activity at human CB2 receptor expressed in CHO cells assessed as cAMP accumulation incubated for 30 mins by time-resolved FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50090963(US9290451, 86 | CHEMBL3582018)
Affinity DataEC50:  33.1nMT: 2°CAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50090963(US9290451, 86 | CHEMBL3582018)
Affinity DataKi:  179nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50090963(US9290451, 86 | CHEMBL3582018)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50090963(US9290451, 86 | CHEMBL3582018)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50090963(US9290451, 86 | CHEMBL3582018)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human CB1 receptor expressed in CHO cells assessed as cAMP accumulation incubated for 30 mins by time-resolved FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed