BDBM50090967 CHEMBL3582036

SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cn(nc4C(F)(F)F)-c4ccccc4)cc3F)c2s1

InChI Key InChIKey=CSHKPXBUKCDALG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090967   

TargetMacrophage-stimulating protein receptor(Human)
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090967(CHEMBL3582036)
Affinity DataIC50: 95nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090967(CHEMBL3582036)
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed