BDBM500910 (S)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((5-(3- hydroxytetra- hydrofuran-3- yl)pyridin-2- yl)amino)isoin- dolin-1-one::US11021481, Compound I-574::US11078201, Compound I-574::US11548890, Compound I-574

SMILES O[C@@]1(CCOC1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnc3cc(F)ccn23)nc1

InChI Key InChIKey=JYUVKXQPUVSWPX-XMMPIXPASA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500910   

LigandPNGBDBM500910((S)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500910((S)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500910((S)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500910((S)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500910((S)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent