BDBM50091047 CHEMBL3582110

SMILES Cc1noc(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)cc1Cl

InChI Key InChIKey=WOYXGESYPYMTAQ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091047   

TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091047(CHEMBL3582110)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human glucocorticoid receptor transfected in CHOK1 cells assessed as inhibition of dexamethasone-induced receptor transcriptio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091047(CHEMBL3582110)
Affinity DataKi:  151nMAssay Description:Displacement of [3H]-dexamethasone from cytosolic fraction of human recombinant glucocorticoid receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091047(CHEMBL3582110)
Affinity DataKi:  403nMAssay Description:Displacement of [3H]-progesterone from cytosolic fraction of human recombinant progesterone-B receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091047(CHEMBL3582110)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]-aldosterone from cytosolic fraction of human recombinant mineralocorticoid receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed