BDBM50091203 4-[2-(5-Methyl-pyridin-2-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide::CHEMBL327078

SMILES Cc1ccc(nc1)-c1nc(cn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=HIVJERZCQSOIRA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091203   

TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50091203(4-[2-(5-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 724nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50091203(4-[2-(5-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091203(4-[2-(5-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 3.02E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50091203(4-[2-(5-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 7.24E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed